Original article Impact of rs12979860 polymorphism on liver morphology in chronic HCV infection
نویسندگان
چکیده
منابع مشابه
Impact of rs12979860 polymorphism on liver morphology in chronic HCV infection
AIM OF THE STUDY To determine distribution of rs12979860 genotypes, their correlations with viral load as well as inflammatory activity and stage of liver fibrosis in patients infected with HCV genotype 1. MATERIAL AND METHODS The study included 132 patients infected with HCV genotype 1b. Serum viral loads were obtained with the PCR method. Rs12979860 polymorphisms were determined by sequenci...
متن کاملIL28B rs12979860 gene polymorphism in Egyptian patients with chronic liver disease infected with HCV.
BACKGROUND Egypt has one of the highest prevalences of hepatitis C virus (HCV) infection worldwide. Although the IL28B gene polymorphism has been shown to modify the course of chronic HCV infection, this has not been properly assessed in the Egyptian population. MATERIALS AND METHODS The IL28B rs12979860 single nucleotide polymorphism (SNP) was therefore examined in 256 HCV-infected Egyptian ...
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Original Contribution POSITIVE HBV DNA IN LIVER SAMPLES IN PATIENTS WITH CHRONIC HCV INFECTION
PURPOSE: To determine prevalence of positive HBV DNA in liver tissue samples in patients with chronic HCV infection (CHCV) and to investigate whether there is an association between it and underlying clinical condition. METHODE: For the period 2004 – 2010 in the Gastroenterology Clinic at the Military Medical Academy – Sofia, 96 patients CHCV (77% males, 23% females, mean age 50, 5 ± 10, 02 yea...
متن کاملOriginal Article: Investigation of Bcl-2 and PCNA in Hepatocellular Carcinoma: Relation to Chronic HCV.
BACKGROUND AND OBJECTIVE Bcl-2 family members can be functionally divided into anti-apoptotic and proapoptotic groups. The balance between these two groups may determine the fate of tumor cells. In hepatocellular carcinoma (HCC), this balance is often tilted towards the anti-apoptotic members in tumor cells, leading to resistance to cell death and rapid proliferation. MATERIAL AND METHODS In ...
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ژورنال
عنوان ژورنال: Clinical and Experimental Hepatology
سال: 2015
ISSN: 2392-1099
DOI: 10.5114/ceh.2015.51374